Rational use of drugs to alleviate adverse outcomes caused by COVID-19 quarantine in women with intrahepatic cholestasis of pregnancy.

Purpose: This study aimed to investigate the impacts of home quarantine on pregnancy outcomes of women with intrahepatic cholestasis of pregnancy (ICP) during the COVID-19 outbreak and whether the rational use of drugs will change these impacts. Methods: This multi-center study was conducted to compare the pregnancy outcomes in women with ICP between the home quarantine group and the non-home quarantine group in southwest China. Propensity score matching was performed to confirm the pregnancy outcomes of the medication group and the non-medication group in women with ICP during the epidemic period. Results: A total of 3,161 women with ICP were enrolled in this study, including 816 in the home quarantine group and 2,345 in the non-home quarantine group. Women with ICP in the home quarantine group had worse pregnancy outcomes, such as a growing risk of gestational diabetes mellitus A1, fetal growth restriction, pre-eclampsia, preterm delivery, and even stillbirth. Drug therapy could alleviate some adverse pregnancy outcomes caused by home quarantine, including pre-eclampsia, preterm delivery, and meconium-stained amniotic fluid. Conclusion: COVID-19 quarantine would increase the incidence of ICP and lead to adverse pregnancy outcomes in women with ICP. The rational use of drugs reduced some obstetrical complications and improved partial pregnancy outcomes. Our findings suggested that the government and hospitals should enhance their management and life guidance for women with ICP and speed up developing home quarantine guidelines.

Development of a Three-Dimensional Optical Verification Technology without Environmental Pollution for Metal Components with Different Surface Properties.

Nowadays, the optical measuring approach is widely used in the precision machining industry due to high measurement efficiency. In the industry, measuring devices play a crucial role in the field of quality assurance. In practical engineering, the green measurement approach indeed plays an important role in the industry currently. In this study, a state-of-the-art green technique for three-dimensional (3D) optical measurements without environmental pollution is demonstrated, which is an environmentally friendly optical measurement method. This method can perform precise optical measurement without matte coatings. This work dealt with the possibility of measuring four metal components that were not sprayed with anything. The differences in the optical measurement results between with and without matte coatings were investigated and analyzed. It was found that the research result has practical value in the precision machining industry because average size errors of the four measurement objects with different surface properties can be controlled at about 3 µm, 0.1 µm, 0.5 µm, and 9 µm. A technical database with industrial value was established for optical measurements of metal components with different surface properties without matte coatings, which can serve as an alternative to the conventional 3D optical measurement.

An Environmentally-Friendly Three-Dimensional Computer-Aided Verification Technique for Plastic Parts.

Plastic components play a significant role in conserving and saving energy. Plastic products provide some advantages over metal, including reducing part weight, manufacturing costs, and waste, and increasing corrosion resistance. Environmental sustainability is one of the sustainable development goals (SDGs). Currently, the non-contact computer-aided verification method is frequently employed in the plastic industry due to its high measurement efficiency compared with the conventional contact measuring method. In this study, we proposed an innovative, green three-dimensional (3D) optical inspection technology, which can perform precise 3D optical inspection without spraying anything on the component surface. We carried out the feasibility experiments using two plastic parts with complex geometric shapes under eight different proposed measurement strategies that can be adjusted according to the software interface. We studied and analyzed the differences in 3D optical inspection for building an empirical technical database. Our aim in this study is to propose a technical database for 3D optical measurements of an object without spraying anything to the component's surface. We found that the research results fulfilled the requirements of the SDGs. Our research results have industrial applicability and practical value because the dimensional average error of the two plastic parts has been controlled at approximately 3 µm and 4.7 µm.